A Third Strand for DNA
from chemistry world
The DNA double helix can under certain conditions accommodate a third strand in its major groove. Researchers in the UK have now presented a complete set of four variant nucleotides that makes it possible to use this phenomenon in gene regulation and mutagenesis.
.....so triplex formation will only work at low pH.
from chemistry world
The DNA double helix can under certain conditions accommodate a third strand in its major groove. Researchers in the UK have now presented a complete set of four variant nucleotides that makes it possible to use this phenomenon in gene regulation and mutagenesis.
.....so triplex formation will only work at low pH.
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